3D Print: Hemoglobin
Download curated files for 3D printing.
3D Model Information
PDB structure used to generate the model file: 4hhb
Model generated with: MolecularMaya/Autodesk Maya
Model physical size (in mm): 71.6 x 62.3 x 57.9
Download 3D Print File (.stl)Additional Models: Heme ligand
Model generated with: MolecularMaya/Autodesk Maya
Model physical size (in mm): 8.2 x 18.1 x 15.8
Additional: Each hemoglobin subunit contains one heme molecule. Print this model 4 times to assemble the complete structure.
Download 3D Print File (.stl)Sample print
Printed on: Ultimaker S3
Model material: PLA
Support material: PVA (water soluble)
Output scale: 100% for hemoglobin, 85% for heme to create an offset for fitting parts
3D Print and Structural Features of Hemoglobin
Hemoglobin transports oxygen in our blood. The protein changes shape based on its oxygenation state with this model (PDB structure 4hhb) capturing the oxygen-free state. PDB structure 3A0G is an example of oxygenated hemoglobin.
Hemoglobin comprises four chains, 2 alpha and 2 beta. The model features distinctive ridges that allow for easy identification of these chains. The alpha subunits were hand-painted in darker red on the model. Each subunit contains a pocket to hold one heme (Image 1).
The heme is a ring-shaped molecule that binds oxygen to its central iron atom. In the example shown, each of the heme molecules was modeled using a piece of pipe cleaner and a 5 mm melty bead to represent the iron (Image 2).
A file for printing the hemes is provided, but the pipe cleaner models are easier to put in and out for demonstrations (Image 3).