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Molecule of the Month illustrations are available under a CC-BY-4.0 license. Attribution should be given to David S. Goodsell and the RCSB PDB. Molecule of the Month articles are copyrighted by the RCSB PDB and the authors of the article. Text can only be reprinted with permission, with attribution, and without the right to manipulate or change its content. To request permission, please contact [email protected].

RCSB PDB Molecule of the Month articles may be referenced using a Digital Object Identifier (DOI) with format: 10.2210/rcsb_pdb/mom_YYYY_MM, where YYYY should be replaced with the year, and MM with the number of the month (one or two digits).

Date ID Title Download Image Image Name
2024
November 299 Malaria Parasite PTEX 6e10.tif
7jgh_7nnh.tif
October 298 Angiotensin and Blood Pressure angiotensin_figure.tif
1O86_MolStar.tif
September 297 Carbon Capture Mechanisms BicA.tif
carboxysome.tif
6tjv.tif
August 296 ESCRT-III 6tz4_figure.tif
7o3z_7o3w.tif
July 295 Ribosome Diversity ribosomes.tif
Initiation.tif
June 294 Injectisome 7ah9_2.tif
Figure_gtgA.tif
May 293 CFTR and Cystic Fibrosis 8eiq.tif
6bqn.tif
April 292 YES Complex 8g02.tif
4jpp.tif
March 291 Hyaluronidases hyal.tif
8fnx_8fyg.tif
February 290 Nanowires 7qv7_figure.tif
GeobacterNanowires.tif
January 289 Mediator 7enc.tif
7enc2.tif
5iyd_figure.tif
2023
December 288 Vitamins 3fpz.tif
7zsc_4bta.tif
2biw.tif
6wv5.tif
FAD.tif
VitD.tif
3w67.tif
November 287 ZAR1 Resistosome 6j5t.tif
model2.tif
October 286 RSV Fusion Glycoprotein 4jhw_3rrr.tif
5udc.tif
September 285 Histone Deacetylases HDACs.tif
6z6p_figure.tif
August 284 ATM and ATR Kinases ATM_ATR.tif
DNADamageSensors.tif
July 283 c-Abl Protein Kinase and Imatinib Figure1.tif
1opk_Figure2.tif
June 282 Odorant Receptors 8f76_Figure.tif
OBP.tif
May 281 Cellulases and Bioenergy Cel7A.tif
Figure2.tif
April 280 MHC I Peptide Loading Complex PLC.tif
Figure2.tif
5ab0_composite.tif
March 279 Anaphase-Promoting Complex / Cyclosome 5a31_label.tif
5g04_label.tif
February 278 SARS-CoV-2 Nucleocapsid and Home Tests nucleocapsid.tif
antibodies.tif
January 277 Plastic-eating Enzymes 5xh3_6qga.tif
5y0m_2zm0.tif
2022
December 276 Click Chemistry 1q83_figure.tif
3cyu_crop.tif
November 275 Actin Branching by Arp2/3 Complex 7tpt_label.tif
2btf_7pdz.tif
October 274 Phytohormone Receptor DWARF14 5hzg_figure.tif
4jym_Figure.tif
September 273 Respiratory Supercomplex Figure1.tif
Figure2.tif
August 272 Secretory Antibodies 3chn_6ue7.tif
6xja.tif
July 271 Non-Homologous End Joining Supercomplexes 1jey.tif
7nfc.tif
7lsy.tif
June 270 Pyruvate Kinase M2 4fxf_twoview.tif
6wp3.tif
May 269 Nicotine, Cancer, and Addiction 6pv7_twoviews.tif
4ejh.tif
April 268 HER2/neu and Trastuzumab Figure1.tif
Figure2.tif
March 267 Vascular Endothelial Growth Factor (VegF) and Angiogenesis 5t89_new.tif
VegF_recolor2.tif
vammin.tif
February 266 Oligosaccharyltransferase 6s7o.tif
6FTI_density.tif
January 265 Golgi Casein Kinase 5yh2.tif
2021CaseinMicelle.tif
2021
December 264 SARS-CoV-2 Spike Variants SWISSmodel_7kj2_label.tif
Variants_new.tif
November 263 Acetohydroxyacid Synthase 6vz8.tif
AHAS.tif
October 262 Fifty Years of Open Access to PDB Structures 1970s.tif
2tbv.tif
2brd.tif
4v4q_1rqu.tif
7cgo.tif
September 261 DNA-Sequencing Nanopores 4uv3_sequencing.tif
Nanopores.tif
August 260 Ribonuclease P 6ahu.tif
ThreeRNaseP.tif
July 259 Designed Proteins and Citizen Science 259-Designed_Proteins_and_Citizen_Science-FoldiProteins.tif
259-Designed_Proteins_and_Citizen_Science-3i1c_3u0s.tif
June 258 Glucocorticoid Receptor and Dexamethasone 258-Glucocorticoid_Receptor_and_Dexamethasone-1m2z_1glu.tif
258-Glucocorticoid_Receptor_and_Dexamethasone-6xk0.tif
May 257 Fetal Hemoglobin 257-Fetal_Hemoglobin-1fdh_4hhb.tif
257-Fetal_Hemoglobin-6ki6_twoviews.tif
April 256 SARS-CoV-2 Spike and Antibodies 256-SARSCoV2_Spike_and_Antibodies-Spike_Antibodies.tif
256-SARSCoV2_Spike_and_Antibodies-nanobodies2.tif
March 255 Cisplatin and DNA 255-Cisplatin_and_DNA-Fig1.tif
255-Cisplatin_and_DNA-Fig2.tif
255-Cisplatin_and_DNA-Fig3.tif
February 254 Cellulose Synthase 254-Cellulose_Synthase-6wlb_composite.tif
254-Cellulose_Synthase-2021PlantCellWall_crop.tif
254-Cellulose_Synthase-2icy_3s27.tif
January 253 Expressome 253-Expressome-6x9q_composite.tif
253-Expressome-6ztm_6x9q.tif
2020
December 252 Hepatitis C Virus Protease/Helicase 252-Hepatitis_C_Virus_ProteaseHelicase-1cu1_label.tif
252-Hepatitis_C_Virus_ProteaseHelicase-4wtg_1zh1_1r7g_2.tif
November 251 Adenylyl Cyclase 251-Adenylyl_Cyclase-6r3q_full.tif
251-Adenylyl_Cyclase-5u6p.tif
October 250 Capsaicin Receptor TRPV1 250-Capsaicin_Receptor_TRPV1-5is0_composite.tif
250-Capsaicin_Receptor_TRPV1-6dmw.tif
September 249 SARS-CoV-2 RNA-dependent RNA Polymerase 249-SARSCoV2_RNAdependent_RNA_Polymerase-6yyt_label.tif
249-SARSCoV2_RNAdependent_RNA_Polymerase-2ahm_2.tif
August 248 Phytosulfokine Receptor 248-Phytosulfokine_Receptor-4z64_Figure.tif
248-Phytosulfokine_Receptor-4mn8_4lsx.tif
July 247 Myelin-associated Glycoprotein 5lf5_composite3.tif
247-Myelinassociated_Glycoprotein-Myelin.tif
247-Myelinassociated_Glycoprotein-1pkq_1bx2.tif
June 246 SARS-CoV-2 Spike 246-SARSCoV2_Spike-6crz_6vxx3.tif
246-Coronavirus_Spike-6vsb_6m17_2.tif
May 245 Spliceosomes 245-Spliceosomes-3jb9.tif
245-Spliceosomes-6n7p.tif
245-Spliceosomes-1mh1_1ryf.tif
April 244 Photosynthetic Supercomplexes 244-Photosynthetic_Supercomplexes-5xnl.tif
244-Photosynthetic_Supercomplexes-6kad_6kac.tif
244-Photosynthetic_Supercomplexes-5zji_6nwa.tif
March 243 Voltage-gated Sodium Channels 242-Voltagegated_Sodium_Channels-6j8j_twoview.tif
242-Voltagegated_Sodium_Channels-6a95_green.tif
February 242 Coronavirus Proteases 243-Coronavirus_Proteases-6lu7.tif
243-Coronavirus_Proteases-1q2w_4ow0.tif
January 241 Twenty Years of Molecules 241-Twenty_Years_of_Molecules-6j4y.tif
241-Twenty_Years_of_Molecules-records.tif
241-Twenty_Years_of_Molecules-2or1.tif
241-Twenty_Years_of_Molecules-6mam.tif
241-Twenty_Years_of_Molecules-6by7.tif
241-Twenty_Years_of_Molecules-CyclicBeauty.tif
2019
December 240 Hypoxia-Inducible Factors 240-HypoxiaInducible_Factors-1lqb_composite.tif
240-HypoxiaInducible_Factors-4zpr.tif
November 239 Phospholipase A2 239-Phospholipase_A2-1bp2.tif
239-Phospholipase_A2-1bp2_1cjy.tif
October 238 Ribonucleotide Reductase 238-Ribonucleotide_Reductase-1mrr_3r1r.tif
238-Ribonucleotide_Reductase-3uus.tif
September 237 Nanodiscs and HDL 237-Nanodiscs_and_HDL-4v6m.tif
237-Nanodiscs_and_HDL-6clz.tif
August 236 Cyclin and Cyclin-dependent Kinase 236-Cyclin_and_Cyclindependent_Kinase-1fin.tif
236-Cyclin_and_Cyclindependent_Kinase-CDKinhibitors.tif
July 235 AMPA Receptor 235-AMPA_Receptor-3kg2_composite.tif
235-AMPA_Receptor-iGluR.tif
June 234 MDM2 and Cancer 234-MDM2_and_Cancer-MDM2_painting.tif
234-MDM2_and_Cancer-MDM2.tif
May 233 S-Nitrosylated Hemoglobin 233-SNitrosylated_Hemoglobin-1buw.tif
233-SNitrosylated_Hemoglobin-2ifq.tif
April 232 Proteins and Biominerals 231-Proteins_and_Biominerals-1q8h_4uxm.tif
231-Proteins_and_Biominerals-4jj0.tif
March 231 Measles Virus Proteins 231-Measles_Virus_Proteins-measles.tif
232-Measles_Virus_Proteins-4uft.tif
February 230 Initiation Factor eIF4E 230-Initiation_Factor_eIF4E-1ap8_1rf8.tif
230-Initiation_Factor_eIF4E-complexes.tif
January 229 Fluorescent RNA Aptamers 229-Fluorescent_RNA_AptamersSpinach_fluorescent_aptamer_with_RNA_in_light_orange_and_fluorophore_in_green-4kzd.tif
229-Fluorescent_RNA_AptamersSpinach_fluorescent_aptamer_with_RNA_in_light_orange_and_fluorophore_in_green-fluorescent_aptamers.tif
2018
December 228 Directed Evolution of Enzymes 228-Directed_Evolution_of_Enzymes-5ucw.tif
228-Directed_Evolution_of_Enzymes-3wwj.tif
228-Directed_Evolution_of_Enzymes-1wdw_6am8.tif
November 227 Telomerase 227-Telomerase-6d6v.tif
227-Telomerase-143d.tif
October 226 Aminoglycoside Antibiotics and Resistance 226-Aminoglycoside_Antibiotics_and_Resistance-1fjg.tif
226-Aminoglycoside_Antibiotics_and_Resistance-4ox9.tif
September 225 Phytase 225-Phytase-1dkq_phyticacid.tif
225-Phytase-phytases.tif
August 224 Legumain 224-Legumain-4awb.tif
224-Legumain-legumains.tif
July 223 Piezo1 Mechanosensitive Channel 223-Piezo1_Mechanosensitive_Channel-6b3r.tif
223-Piezo1_Mechanosensitive_Channel-3um7_5vkq.tif
June 222 Proteins and Nanoparticles 221-Proteins_and_Nanoparticles-5et3_motm.tif
221-Proteins_and_Nanoparticles-4prq.tif
221-Proteins_and_Nanoparticles-5oeh_3nkx.tif
May 221 Human Papillomavirus and Vaccines 222-Human_Papillomavirus_and_Vaccines-3j6r-6bt3.tif
222-Human_Papillomavirus_and_Vaccines-4xr8.tif
April 220 Dehalogenases 220-Dehalogenases-4ur0.tif
220-Dehalogenases-dehalogenases.tif
March 219 Vacuolar ATPase 219-Vacuolar_ATPase-5vox.tif
219-Vacuolar_ATPase-ATPases.tif
February 218 EPSP Synthase and Weedkillers 218-EPSP_Synthase_and_Weedkillers-2gg4_2gga.tif
218-EPSP_Synthase_and_Weedkillers-2p1n.tif
January 217 Opioid Receptors 217-Opioid_Receptors-4dkl.tif
217-Opioid_Receptors-3fvy_5ee3.tif
2017
December 216 Biodegradable Plastic 216-Biodegradable_Plastic-5t6o_composite.tif
216-Biodegradable_Plastic-4o9c_3vzs.tif
November 215 Aspartate Transcarbamoylase 215-Aspartate_Transcarbamoylase-5at1.tif
215-Aspartate_Transcarbamoylase-CAD.tif
October 214 Chimeric Antigen Receptors 214-Chimeric_Antigen_Receptors-CAR.tif
214-Chimeric_Antigen_Receptors-CART_2017.tif
September 213 Sirtuins 213-Sirtuins-4iao.tif
213-Sirtuins-5btr_5mf6.tif
August 212 Glutathione Transferases 212-Glutathione_Transferases-3gss.tif
212-Glutathione_Transferases-3zml_3zmk.tif
July 211 Pilus Machine 211-Pilus_Machine-3jc8.tif
211-Pilus_Machine-3jc8_action.tif
June 210 Adenine Riboswitch in Action 210-Adenine_Riboswitch_in_Action-5e54_5swe.tif
210-Adenine_Riboswitch_in_Action-5e54_5swe_lattice.tif
May 209 Tissue Transglutaminase and Celiac Disease 209-Tissue_Transglutaminase_and_Celiac_Disease-2q3z_3ly6.tif
209-Tissue_Transglutaminase_and_Celiac_Disease-1s9v_5ks9.tif
April 208 Glucose Transporters 208-Glucose_Transporters-4pyp_4zwc.tif
208-Glucose_Transporters-1pv6_1pw4.tif
March 207 Photoactive Yellow Protein 207-Photoactive_Yellow_Protein-2pyp.tif
207-Photoactive_Yellow_Protein-2zoi.tif
February 206 Globin Evolution 206-Globin_Evolution-Myoglobins.tif
206-Globin_Evolution-Globins.tif
206-Globin_Evolution-3vrf.tif
January 205 Nuclear Pore Complex 205-Nuclear_Pore_Complex-5a9q_5ijn.tif
205-Nuclear_Pore_Complex-5dis.tif
2016
December 204 PD-1 (Programmed Cell Death Protein 1) 203-PD1_Programmed_Cell_Death_Protein_1-3bik_3bp5.tif
203-PD1_Programmed_Cell_Death_Protein_1-5dk3_5jxe.tif
November 203 Aminopeptidase 1 and Autophagy 203-Aminopeptidase_1_and_Autophagy-Selective_Autophagy_2016.tif
204-Aminopeptidase_1_and_Autophagy-5jh9_4r8f.tif
October 202 Dipeptidyl Peptidase 4 202-Dipeptidyl_Peptidase4-1nu8.tif
202-Dipeptidyl_Peptidase4-Substrates2.tif
September 201 Isoprene Synthase 201-Isoprene_Synthase-3n0g.tif
201-Isoprene_Synthase-1i9a_1p0n.tif
August 200 Quasisymmetry in Icosahedral Viruses 200-Quasisymmetry_in_Icosahedral_Viruses-Quasisymmetry.tif
200-Quasisymmetry_in_Icosahedral_Viruses-1sva_2btv.tif
July 199 Monellin 199-Monellin-SuperSweet.tif
199-Monellin-SweetReceptor.tif
June 198 Beta-galactosidase 198-betaGalactosidase-1jz8.tif
198-Betagalactosidase-bgal_2015_Multicolor_highRes_Subramaniam.tif
May 197 Zika Virus 197-Zika_Virus-5ire_glyc.tif
197-Zika_Virus-ZikaVirus.tif
April 196 Lead Poisoning 196-Lead_Poisoning-1qnv.tif
196-Lead_Poisoning-lead.tif
March 195 RAF Protein Kinases 195-Raf_Protein_Kinases-raf.tif
195-Raf_Protein_Kinases-1uwj.tif
February 194 Designer Insulins 194-Designer_Insulins-1trz.tif
194-Designer_Insulins-4ajx.tif
January 193 Siderocalin 193-Siderocalin-3cmp_composite.tif
193-Siderocalin-1lfg_3eyc.tif
2015
December 192 Vancomycin 192-Vancomycin-1fvm.tif
192-Vancomycin-3se7.tif
November 191 Glutamate-gated Chloride Receptors 191-GlutamateGatedChlorideReceptors_3rif.tif
191-GlutamateGatedChlorideReceptors_4hfe_3jad.tif
October 190 Two-component Systems 190-TwoComponentSystems_2c2a_3by8.tif
190-TwoComponentSystems_1kgs_1gxp_1zes.tif
September 189 Amyloids 189-Amyloids_2m4j.tif
189-Amyloids_amyloids.tif
August 188 Tetrahydrobiopterin Biosynthesis 188-TetrahydrobiopterinBiosynthesis_1gtp_1gtq_1sep.tif
188-TetrahydrobiopterinBiosynthesis_1dcp_1dhr.tif
July 187 New Delhi Metallo-Beta-Lactamase 187-New_Delhi_MetalloBetaLactamase-4eyl.tif
187-New_Delhi_MetalloBetaLactamase-3rxw.tif
June 186 Receptor for Advanced Glycation End Products 186-ReceptorForAdvancedGlycationEndProducts_4lp5_figure.tif
186-ReceptorForAdvancedGlycationEndProducts_3b75_figure.tif
May 185 Titin 185-Titin_sarcomere_titin.tif
185-Titin_1ya5.tif
April 184 Glucagon 184-Glucagon_glucagonreceptor.tif
184-Glucagon_proglucagon.tif
March 183 Phototropin 183-Phototropin_phototropin.tif
183-Phototropin_Vivid.tif
February 182 Insulin Receptor 182-InsulinReceptor_insulinreceptor.tif
182-InsulinReceptor_3w14_composite.tif
January 181 Cascade and CRISPR 181-CascadeAndCRISPR_1vy8.tif
181-CascadeAndCRISPR_CasProteins.tif
181-CascadeAndCRISPR_4un3.tif
2014
December 180 TAL Effectors 180-TALEffectors_3ugm.tif
180-TALEffectors_TALEN.tif
November 179 Methyl-coenzyme M Reductase 179-MethylCoenzymeMReductase_1mro.tif
179-MethylCoenzymeMReductase_1mro_tools.tif
October 178 Ebola Virus Proteins 178-Ebola_Virus_Proteins-EbolaProteins2018.tif
178-Ebola_Virus_Proteins-5z9w.tif
178-EbolaVirusProteins_VP40.tif
September 177 Apoptosomes 177-Apoptosomes_human_apoptosome.tif
177-Apoptosomes_apoptosomes.tif
August 176 Dynein 176-Dynein_3vkh-label.tif
176-Dynein_3j1t.tif
July 175 Microtubules 175-Microtubules_3j2u.tif
175-Microtubules_1ffx.tif
June 174 GFP-like Proteins 174-GFPLikeProteins_1g7k.tif
174-GFPLikeProteins_GFP-like_Proteins.tif
May 173 Aquaporin 173-Aquaporin_1fqy.tif
173-Aquaporin_1fx8_pmv.tif
April 172 RecA and Rad51 172-RecAAndRad51_recA_filament.tif
172-RecAAndRad51_1w36.tif
March 171 Neurotransmitter Transporters 171-NeurotransmitterTransporters_4m48.tif
171-NeurotransmitterTransporters_2nwx.tif
February 170 Broadly Neutralizing Antibodies 170-BroadlyNeutralizingAntibodies_4nco_bnAb.tif
170-BroadlyNeutralizingAntibodies_HA_bnAb.tif
January 169 HIV Envelope Glycoprotein 169-HIVEnvelopeGlycoprotein_4nco_composite.tif
169-HIVEnvelopeGlycoprotein_1gc1_composite.tif
2013
December 168 DNA Helicase 168-DNAHelicase_4esv.tif
168-DNAHelicase_3r8f_helix.tif
November 167 SNARE Proteins 167-SNAREProteins_1sfc_1br0.tif
167-SNAREProteins_1nsf.tif
October 166 Proteasome 166-Proteasome_4b4t_dimer.tif
166-Proteasome_1fnt_3l5q.tif
September 165 Designed Protein Cages 165-DesignedProteinCages_3vdx_4egg.tif
165-DesignedProteinCages_3tom.tif
August 164 Serotonin Receptor 164-SerotoninReceptor_4iar.tif
164-SerotoninReceptor_3gwv.tif
July 163 HIV Capsid 163-HIVCapsid_capsid_composite.tif
163-HIVCapsid_2lm3_1ak4_1e6j.tif
June 162 Dermcidin 162-Dermcidin_2ymk_twoviews.tif
162-Dermcidin_1dfn_2k6o.tif
May 161 Ricin 161-Ricin_2aai.tif
161-Ricin_3u5d_3u5e.tif
161-Ricin_immunotoxin.tif
April 160 Actinomycin 160-Actinomycin_173d_composite.tif
160-Actinomycin_1k4t.tif
March 159 Erythrocruorin 159-Erythrocruorin_2gtl.tif
159-Erythrocruorin_hemoglobins.tif
February 158 Proton-Gated Urea Channel 158-ProtonGatedUreaChannel_3ux4.tif
158-ProtonGatedUreaChannel_1e9y.tif
January 157 Transfer-Messenger RNA 157-TransferMessengerRNA_3iyr_composite.tif
157-TransferMessengerRNA_3j18_3j19_composite.tif
2012
December 156 ABO Blood Type Glycosyltransferases 156-ABOBloodTypeGlycosyltransferases_3i0g_composite.tif
156-ABOBloodTypeGlycosyltransferases_1lu1_2j1u_2obs.tif
November 155 Vitamin D Receptor 155-VitaminDReceptor_VDRcryo.tif
155-VitaminDReceptor_3c6g_1j78.tif
October 154 Citric Acid Cycle 154-CitricAcidCycle_citricacidcycle.tif
154-CitricAcidCycle_1cts.tif
154-CitricAcidCycle_7acn-composite.tif
154-CitricAcidCycle_3blw.tif
154-CitricAcidCycle_OGDH.tif
154-CitricAcidCycle_2fp4_1cqi.tif
154-CitricAcidCycle_1nek-composite.tif
154-CitricAcidCycle_1fuo.tif
154-CitricAcidCycle_1mld_5mdh.tif
September 153 Pyruvate Dehydrogenase Complex 153-PyruvateDehydrogenaseComplex_pyruvatedehydrogenase.tif
153-PyruvateDehydrogenaseComplex_1w85_composite.tif
August 152 cAMP-dependent Protein Kinase (PKA) 152-cAMP-dependentProteinKinase_PKA.tif
152-cAMP-dependentProteinKinase_1xp0.tif
July 151 Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) 151-HGPRT_1hmp.tif
151-HGPRT_1cjb.tif
June 150 Sliding Clamps 150-SlidingClamps_3u5z_open.tif
150-SlidingClamps_1ul1.tif
May 149 Leptin 149-Leptin_1ax8.tif
149-Leptin_1ron.tif
April 148 Ras Protein 148-RasProtein_5p21.tif
148-RasProtein_Ras.tif
March 147 Rhodopsin 147-Rhodopsin_1f88.tif
147-Rhodopsin_3fsn.tif
February 146 Aminoglycoside Antibiotics 146-AminoglycosideAntibiotics_3frh_3pb3.tif
146-AminoglycosideAntibiotics_aminoglycoside_modifying_enzymes.tif
January 145 Messenger RNA Capping 145-MessengerRNACapping_3kyh_1ri1.tif
145-MessengerRNACapping_2qkm_1st0.tif
2011
December 144 Complex I 144-ComplexI_3m9s_3rko.tif
144-ComplexI_1zcd.tif
November 143 Toll-like Receptors 143-TollLikeReceptors_3fxi_2j67.tif
143-TollLikeReceptors_3ciy.tif
October 142 PDB Pioneers 142-PDBPioneers_oxygencarrier.tif
142-PDBPioneers_enzymes.tif
142-PDBPioneers_electroncarrier.tif
September 141 O-GlcNAc Transferase 141-OGlcNAcTransferase_3pe4_1w3b.tif
141-OGlcNAcTransferase_2cbj.tif
August 140 Rhomboid Protease GlpG 140-RhomboidProteaseGlpG_2nrf_membrane.tif
140-RhomboidProteaseGlpG_3b4r_3s0x.tif
July 139 DNA Methyltransferases 139-DNAMethylases_DNMT.tif
139-DNAMethylases_1mht.tif
June 138 Glucansucrase 138-Glucansucrase_3aic.tif
138-Glucansucrase_3aie_1smd.tif
May 137 Cytochrome bc1 137-Cytochromebc1_3h1j.tif
137-Cytochromebc1_1vf5.tif
April 136 Nanobodies 136-Nanobodies_antibody_nanobody.tif
136-Nanobodies_1mel_complex.tif
March 135 Integrase 135-Integrase_3os1_composite.tif
February 134 Integrin 134-Integrin_1jv2-2k9j-1m8o.tif
134-Integrin_integrins.tif
January 133 Nitric Oxide Synthase 133-NitricOxideSynthase_nNOS.tif
133-NitricOxideSynthase_sGC.tif
2010
December 132 Adenovirus 132-Adenovirus_adenovirus.tif
132-Adenovirus_adenovirus_clip.tif
November 131 Inteins 131-Inteins_1jva.tif
131-Inteins_1lws_1am2.tif
October 130 Riboswitches 130-Riboswitches_1u8d.tif
130-Riboswitches_riboswitches.tif
September 129 Isocitrate Dehydrogenase 129-IsocitrateDehydrogenase_3blw_9icd.tif
129-IsocitrateDehydrogenase_3lcb.tif
August 128 Interferons 128-Interferons_interferons.tif
128-Interferons_3bes.tif
July 127 Crystallins 127-Crystallins.tif
June 126 Epidermal Growth Factor 126-EpidermalGrowthFactor_EGFR.tif
126-EpidermalGrowthFactor_1ptu.tif
May 125 Parvoviruses 125-Parvoviruses_1fpv_2cas.tif
125-Parvoviruses_1s58.tif
April 124 Concanavalin A and Circular Permutation 124-ConcanavalinACircularPermutation_1cvn.tif
124-ConcanavalinACircularPermutation_3cna.tif
March 123 P-glycoprotein 123-P-glycoprotein_3g61_composite.tif
123-P-glycoprotein_3g61_1bln.tif
February 122 Enhanceosome 122-Enhanceosome_enhanceosome.tif
122-Enhanceosome_CBP.tif
January 121 Ribosome 121-70SRibosomes_2wdk_2wdl_front.tif
initiation.tif
121-70SRibosomes_elongation.tif
121-70SRibosomes_termination.tif
121-70SRibosomes_antibiotics.tif
2009
December 120 Antifreeze Proteins 120-AntifreezeProteins_1kdf.tif
120-AntifreezeProteins_antifreeze.tif
November 119 Designed DNA Crystal 119-DesignedDNACrystal_3gbi_composite.tif
119-DesignedDNACrystal_309d.tif
October 118 Sodium-Potassium Pump 118-SodiumPotassiumPump_2zxe_composite.tif
118-SodiumPotassiumPump_2zxe_1su4_3b8c.tif
September 117 Xanthine Oxidoreductase 117-XanthineOxidoreductase_1fo4_composite.tif
117-XanthineOxidoreductase_1r4u_composite.tif
August 116 Sulfotransferases 116-Sulfotransferases_sulfotransferases.tif
116-Sulfotransferases_APSenzymes.tif
July 115 Beta-secretase 115-betaSecretase_1sgz_1py1.tif
115-betaSecretase_1py1.tif
June 114 Vaults 114-Vaults_vaults.tif
114-Vaults_containers.tif
May 113 Influenza Neuraminidase 113-Influenza_Neuraminidase-neuraminidases.tif
113-Influenza_Neuraminidase-1nca.tif
April 112 Oct and Sox Transcription Factors 112-TranscriptionFactors_1gt0_composite.tif
112-TranscriptionFactors_1nkp_2ebt.tif
March 111 Hydrogenase 111-Hydrogenases_composite.tif
111-Hydrogenases_1e08.tif
February 110 Auxin and TIR1 Ubiquitin Ligase 110-AuxinandTIR1UbiquitinLigase_2p1p.tif
110-AuxinandTIR1UbiquitinLigase_1xmb.tif
January 109 Tobacco Mosaic Virus 109-TobaccoMosaicVirus_2tmv_composite.tif
109-TobaccoMosaicVirus_1ei7.tif
2008
December 108 Hsp90 108-Hsp90-2cg9_composite.tif
108-Hsp90-2cg9_2ioq.tif
November 107 Mechanosensitive Channels 107-MechanosensitiveChannels-2oau_composite.tif
107-MechanosensitiveChannels-2oar_composite.tif
October 106 Poly(A) Polymerase 106-Poly-A-Polymerase-1fa0.tif
106-Poly-A-Polymerase-1cvj.tif
September 105 Ribonuclease A 105-Ribonuclease-A-5rsa.tif
105-Ribonuclease-A-2fk6_2ez6.tif
August 104 Selenocysteine Synthase 104-SelenocysteineSynthase-3bc8_2yye.tif
104-SelenocysteineSynthase-1wb1_2uwm.tif
July 103 Dengue Virus 103-DengueVirus-1k4r.tif
103-DengueVirus-nonstructuralproteins.tif
June 102 Lactate Dehydrogenase 102-LactateDehydrogenase-3ldh.tif
102-LactateDehydrogenase-1lth.tif
May 101 Prions 101-Prions-PrP.tif
101-Prions-2rnm.tif
April 100 Adrenergic Receptors 100-AdrenergicReceptors-2rh1.tif
100-AdrenergicReceptors-backbone.tif
March 99 Cadherin 99-Cadherin-1l3w-1i7x.tif
99-Cadherin-1l3w-1q5a-1q5c.tif
February 98 Small Interfering RNA (siRNA) 98-SmallInterferingRNA-siRNA.tif
98-SmallInterferingRNA-1r9f.tif
January 97 Circadian Clock Proteins 97-CircadianClockProteins-Kai-proteins.tif
97-CircadianClockProteins-1cjw.tif
2007
December 96 Oxidosqualene Cyclase 96-OxidosqualeneCyclase-1w6k.tif
96-OxidosqualeneCyclase-1hwk.tif
November 95 Multidrug Resistance Transporters 95-MultidrugResistanceTransporter-2onj.tif
95-MultridrigResistanceTransporter-multidrugtransporters.tif
October 94 Superoxide Dismutase 94-SuperoxideDismutase-2sod.tif
94-SuperoxideDismutase-SODs.tif
September 93 Citrate Synthase 93-CitrateSynthase-1cts-2cts.tif
93-CitrateSynthase-1nxg.tif
August 92 Anabolic Steroids 92-AnabolicSteroids-1d2s.tif
92-AnabolicSteroids-1xf0.tif
July 91 Thymine Dimers 91-ThymineDimers-1n4e.tif
91-ThymineDimers-1vas-1tez.tif
June 90 Fatty Acid Synthase 90-FattyAcidSynthase-fas.tif
90-FattyAcidSynthase-fasII-composite.tif
May 89 Aconitase and Iron Regulatory Protein 1 89-AconitaseandIronRegulatoryProtein1-2b3y-2ipy.tif
89-AconitaseandIronRegulatoryProtein1-moonlighting.tif
April 88 Clathrin 88-Clathrin-1xi4-composite.tif
88-Clathrin-ap2-composite.tif
March 87 Zinc Fingers 87-ZincFingers-1tf6-1un6.tif
87-ZincFingers-zincfingers.tif
February 86 Exosomes 86-Exosomes-2nn6.tif
86-Exosomes-2a1s-1st0.tif
January 85 Importins 85-Importins-1qgk-composite.tif
85-Importins-2bku-1wa5.tif
2006
December 84 Transposase 84-Transposase-1muh-tube.tif
84-Transposase-1z1g-composite.tif
November 83 Fibrin 83-Fibrin-1m1j-composite.tif
83-Fibrin-1m1j-1fzc.tif
October 82 Cytochrome p450 82-Cytochromep450-1w0e-2j0d.tif
82-Cytochromep450-1ea1-1e6e.tif
September 81 Elongation Factors 81-ElongationFactors-1ttt.tif
81-ElongationFactors-1efu.tif
81-ElongationFactors-1dar-1ttt.tif
August 80 AAA+ Proteases 80-AAA+Proteases-1yyf.tif
80-AAA+Proteases-AAAproteins.tif
July 79 Amyloid-beta Precursor Protein 79-Amyloid-betaPrecursorProtein-app-composite.tif
79-Amyloid-betaPrecursorProtein-1fkn.tif
June 78 Luciferase 78-Luciferase-2d1s-composite.tif
78-Luciferase-1brl-1vpr.tif
May 77 Glucose Oxidase 77-GlucoseOxidase-gpe-composite.tif
77-GlucoseOxidase-1gco-1cq1.tif
April 76 Hemagglutinin 76-Hemagglutinin-1ruz-membrane.tif
76-Hemagglutinin-HA-action.tif
March 75 Tissue Factor 75-TissueFactor-2hft-composite.tif
75-TissueFactor-1dan-composite.tif
February 74 Alpha-amylase 74-alpha-Amylase-1ppi.tif
74-alpha-Amylase-industrial.tif
January 73 Topoisomerases 73-Topoisomerases-1a36-composite.tif
73-Topoisomerases-1bgw-1ei1.tif
2005
December 72 ATP Synthase 72-ATPSynthase-ATPsynthase.tif
72-ATP_Synthase-6b8h.tif
November 71 Acetylcholine Receptor 71-AcetylcholineReceptor-2bg9-composite.tif
71-AcetycholineReceptor-1yi5.tif
October 70 Designer Proteins 70-DesignerProteins-1qys-composite.tif
70-DesignerProteins-bundles.tif
September 69 Cholera Toxin 69-CholeraToxin-1xtc-composite.tif
69-CholeraToxin-toxins.tif
August 68 Neurotrophins 68-Neurotrophins-1bet.tif
68-Neurotrophins-receptors.tif
July 67 TATA-Binding Protein 67-TATA-BindingProtein-1cdw.tif
67-TATA-BindingProtein-TF.tif
June 66 Carotenoid Oxygenase 66-CarotenoidOxygenase-2biw-composite.tif
66-CartenoidOxygenase-1jb0-1f88.tif
May 65 Self-splicing RNA 65-Self-SplicingRNA-1u6b.tif
65-Self-SplicingRNA-1mme.tif
April 64 Kinesin 64-Kinesin-3kin-composite.tif
64-Kinesin-3kin-2ncd.tif
March 63 T-Cell Receptor 63-T-CellReceptor-1tcr.tif
63-T-CellReceptor-MHC.tif
February 62 Major Histocompatibility Complex 62-MajorHistocompatibilityComplex-1hsa.tif
62-MajorHistocompatibilityComplex-1hsa-1dlh.tif
Figure3.tif
January 61 Phenylalanine Hydroxylase 61-PhenylalanineHydroxylase-2pah-1phz.tif
61-PhenylalanineHydroxylase-hydroxylases.tif
2004
December 60 Ubiquitin 60-Ubiquitin-ubiquitin.tif
60-Ubiquitin-enzymes.tif
60-Ubiquitin-1fnt.tif
November 59 Photosystem II 59-PhotosystemII-1s5l-chain.tif
59-PhotosystemII-antenna.tif
October 58 G Proteins 58-G_Proteins-1gg2.tif
58-G_Proteins-G-Protein.tif
September 57 Catalase 57-Catalase-7cat.tif
57-Catalase-catalases.tif
August 56 Caspases 56-Caspases-caspases.tif
56-Caspases-CAD.tif
July 55 DNA Ligase 55-DNALigase-1a0i-1dgs.tif
55-DNALigase-1NHEJ-label.tif
June 54 Acetylcholinesterase 54-Acetylcholinesterase-1acj-composite.tif
54-Acetylcholinesterase-1b41-1eve.tif
May 53 Serpins 53-Serpins-1psi.tif
53-Serpins-antitrypsin-action.tif
April 52 Growth Hormone 52-GrowthHormone-hormones.tif
52-GrowthHormone-3hhr-membrane.tif
March 51 Calcium Pump 51-TheCalciumPump-1eul-membrane.tif
51-TheCalciumPumps-calcium-pumps.tif
February 50 Glycolytic Enzymes 50-TheGlycolyticEnzymes-glycolysis.tif
50-TheGlycolyticEnzymes-01-1dgk.tif
50-TheGlycolyticEnzymes-01-1hkg-2yhx.tif
50-TheGlycolyticEnzymes-02-1hox.tif
50-TheGlycolyticEnzymes-03-4pfk.tif
50-TheGlycolyticEnzymes-03-4pfk-6pfk.tif
50-TheGlycolyticEnzymes-04-4ald-1j4e.tif
50-TheGlycolyticEnzymes-05-2ypi.tif
50-TheGlycolyticEnzymes-06-3gpd-1nqo.tif
50-TheGlycolyticEnzymes-07-3pgk-1vpe.tif
50-TheGlycolyticEnzymes-08-3pgm-1eqj.tif
50-TheGlycolyticEnzymes-09-2one.tif
50-TheGlycolyticEnzymes-10-1e0u-1a3w.tif
January 49 Carbonic Anhydrase 49-CarbonicAnhydrase-carbonic-anhydrases.tif
49-CarbonicAnhydrase-1cnw.tif
2003
December 48 Catabolite Activator Protein 48-CataboliteActivatorProtein-1cgp.tif
48-CataboliteActivatorProtein-cap-polymerase.tif
November 47 Simian Virus 40 47-SimianVirus40-1sva-DNA.tif
47-SimianVirus40-T-antigen.tif
October 46 Trypsin 46-Trypsin-serine-proteases.tif
46-Trypsin-trypsinogen.tif
September 45 Estrogen Receptor 45-EstrogenReceptor-1hcq-1a52.tif
45-EstrogenReceptor-tamoxifen.tif
August 44 Calmodulin 44-Calmodulin-3cln.tif
44-Calmodulin-1cfd-1cll.tif
44-Calmodulin-complexes.tif
July 43 Src Tyrosine Kinase 43-SrcTyosineKinase-2src.tif
43-SrcTyrosineKinase-2src-mechanism.tif
June 42 Green Fluorescent Protein (GFP) 42-GreenFlourescentProtein-1gfl-composite.tif
42-GreenFluorescentProtein-1kys-composite.tif
May 41 Hemoglobin 41-Hemoglobin-2dhb.tif
41-Hemoglobin-2hbs-fiber.tif
April 40 RNA Polymerase 40-RNAPolymerase-1i6h-composite.tif
40-RNAPolymerase-1k83.tif
March 39 lac Repressor 39-LacRepressor-lac.tif
39-LacRepressor-lac-DNAloop.tif
39-lac_Repressor-39-LacRepressor-lac-operon.tif
February 38 Potassium Channels 38-PotassiumChannels-1bl8.tif
38-PotassiumChannels.tif
38-PotassiumChannels-2crd.tif
January 37 Serum Albumin 37-SerumAlbumin-1e7i.tif
37-SerumAlbumin-transport.tif
2002
December 36 Cytochrome c 36-Cytochromec-3cyt-twoviews.tif
36-Cytochromec-electron-transport.tif
November 35 Ferritin and Transferrin 35-FerritinandTransferrin-ferritin.tif
35-FerritinandTransferrin-transferrin-and-receptor.tif
October 34 Dihydrofolate Reductase 34-DihydrofolateReductase-7dfr.tif
34-DihydrofolateReductase-3dfr-1dls.tif
September 33 HIV Reverse Transcriptase 33-ReverseTranscriptase-3hvt.tif
33-ReverseTranscriptase-2hmi-label.tif
August 32 Chaperones 32-Chaperones-chaperonin.tif
32-Chaperones-dnaK-prefoldin.tif
July 31 p53 Tumor Suppressor 31-p53TumorSuppressor-p53-unbound.tif
31-p53TumorSuppressor-p53-bound.tif
June 30 Glutamine Synthetase 30-GlutamineSynthetase-1fpy-twoviews.tif
30-GlutamineSynthetase-1fpy-ligands.tif
May 29 Penicillin-binding Proteins 29-Penicillin-bindingProteins-3pte.tif
29-Penicillin-bindingProteins-4blm-3pte.tif
April 28 Anthrax Toxin 28-Anthrax-Toxin.tif
28-AnthraxToxin-1acc-1tzo.tif
March 27 Bacteriorhodopsin 27-Bacteriorhodopsin-1fbb-twoviews.tif
27-Bacteriorhodopsin-two-rhodopsins.tif
February 26 Nitrogenase 26-Nitrogenase-1n2c.tif
26-Nitrogenase-1n2c-clusters.tif
January 25 Thrombin 25-Thrombin-1ppb-transparent.tif
25-Thrombin-activation.tif
25-Thrombin-hirudin.tif
2001
December 24 Glycogen Phosphorylase 24-GlycogenPhosphorylase-6gpb-2views.tif
24-GlycogenPhosphorylase-allostery.tif
November 23 DNA 23-DNA-B-DNA.tif
23-DNA-information.tif
23-DNA-ABZ.tif
October 22 Photosystem I 22-PhotosystemI-1jb0.tif
22-PhotosystemI-1jb0-etc.tif
22-PhotosystemI-reaction-centers.tif
22-PhotosystemI-1jb0-antenna.tif
September 21 Antibodies 21-Antibodies-1igt.tif
21-Antibodies-hyhel-overlap.tif
21-Antibodies-1c1e-reaction.tif
August 20 Poliovirus and Rhinovirus 20-PoliovirusandRhinovirus-picornaviruses.tif
20-PoliovirusandRhinovirus-4rhv-symmetry.tif
20-PoliovirusandRhinovirus-rhinovirus-biology.tif
July 19 Actin 19-Actin-actin18.tif
19-Actin-actin-binding.tif
June 18 Myosin 18-Myosin-1b7t.tif
18-Myosin-painting.tif
18-Myosin-powerstroke.tif
May 17 Cyclooxygenase 17-Cyclooxygenase-1prh-figure.tif
17-Cyclooxygenase-4cox_tunnel.tif
April 16 Aminoacyl-tRNA Synthetases 16-Aminoacyl-tRNASynthetases-1asz.tif
16-Aminoacyl-tRNASynthetases-aaRS.tif
16-Aminoacyl-tRNASynthetases-1ffy.tif
March 15 Transfer RNA 15-TransferRNA-two-trna.tif
February 14 Insulin 14-Insulin-2kqp_4ins.tif
14-Insulin-4ins_2hiu.tif
January 13 Alcohol Dehydrogenase 13-AlcoholDehydrogenase-1htb.tif
13-AlcoholDehydrogenase-two-adh.tif
2000
December 12 Pepsin 12-Pepsin-pepsinogen.tif
12-Pepsin-asp-proteases.tif
November 11 Rubisco 11-Rubisco-1rcx.tif
11-Rubisco-two-forms.tif
October 10 Ribosomal Subunits 10-Ribosome_figure.tif
10-Ribosome-1ffk_front_figure.tif
10-Ribosome-1fka_front_figure.tif
September 9 Lysozyme 9-Lysozyme-2lyz.tif
9-Lysozyme-mutant.tif
August 8 Restriction Enzymes 8-RestrictionEnzymes-EcorI.tif
8-RestrictionEnzymes-stickyends.tif
July 7 Nucleosome 7-Nucleosome-1aoi.tif
7-Nucleosome.tif
June 6 HIV-1 Protease 6-HIV-1Protease-3hvp.tif
6-HIV-1Protease-7hvp_activesite.tif
May 5 Cytochrome c Oxidase 5-CytochromecOxidase-1oco.tif
5-CytochromecOxidase-cytox_composite.tif
5-CytochromecOxidase-1oco_subunit.tif
April 4 Collagen 4-Collagen.tif
4-Collagen-painting_large.tif
March 3 DNA Polymerase 3-DNAPolymerase-1tau.tif
February 2 Bacteriophage phiX174 2-BacteriophagephiX174-mature.tif
2-BacteriophagephiX174-1cd3.tif
January 1 Myoglobin 1-Myoglobin-geis-myoglobin.tif
1-Myoglobin-1pmb_1mbn.tif
1-Myoglobin-1mbo_JSmol.tif
About Molecule of the Month
The RCSB PDB Molecule of the Month by David S. Goodsell (The Scripps Research Institute and the RCSB PDB) presents short accounts on selected molecules from the Protein Data Bank. Each installment includes an introduction to the structure and function of the molecule, a discussion of the relevance of the molecule to human health and welfare, and suggestions for how visitors might view these structures and access further details.More