4. TBP-TFIIB-DNA

On the right-hand side of TBP, Geis depicts Transcription Factor II B (TFIIB) in purple, attached to the other components of the preinitiation complex. Geis positions and colors the purple protein farther back in the painting, depicting its collateral position.

1. apo-TBP
2. TBP-DNA
3. TBP-TFIID-DNA
4. TBP-TFIIB-DNA
5. TBP-TFIIA-DNA
6. RNAP2
7. Myc-Max-DNA
8. HNF-3γ/DNA
Back to main TATA-Binding Protein (TBP) Page

Used with permission from the Howard Hughes Medical Institute (www.hhmi.org). All rights reserved.

Related PDB Entry: 1VOL

Experimental Structure Citation

Nikolov, D. B., Chen, H., Halay, E. D., Usheva, A. A., Hisatake, K., Lee, D. K., Roeder, R. G., & Burley, S. K. (1995). Crystal structure of a TFIIB-TBP-TATA-element ternary complex. Nature, 377, 119-128.

About TBP-TFIIB-DNA

TFIIB is a general transcription factor that joins to form a TBP(TFIID)•TFIIB•DNA complex. After this complex is created, it can then be recognized by a complex of RNA Polymerase II and TFIIF.